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KMID : 1101420160480030196
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Korean Journal of Clinical Laboratory Science
2016 Volume.48 No. 3 p.196 ~ p.201
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A Study on the Relationship between Obesity Factors and NK Cell Activity in White-Collar Females
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Sung Hyun-Ho
Song Chang-Sub
Choi Kwang-Mo
Park Chang-Eun
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Abstract
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An effective strategy for obesity intervention should include demographic, health-related, and work-related factors that are most relevant to the target population. Factors most strongly associated with obesity may differ for groups of individuals across industries or age categories. The purpose of this study was to provide current knowledge about the possible association between psychosocial job stress and immune parameters in blood. We assessed obesity-related parameters as well as the natural killer cell activity (NKCA) in female workers. There was a significant difference in the obesity-related blood parameters, i.e. fasting blood sugar level, according to age (p<0.05). Moreover, it showed a significant difference in NK cell activity between the obese and non-obese factor groups (p<0.05). Pearson correlation analysis demonstrated that NKCA was closely correlated with obesity related factors. In the future, it would have to study the biological changes which increase the activity of the immune factors to the immunological response.
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KEYWORD
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NK cell activity, Obesity, White-collar
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